Two Stony Brook Researchers Among Those Selected to Receive SUNY RF Collaboration Fund Awards Announced by Governor Cuomo
Orlando Scharer investigates targeted cancer therapy; Joanne Davila’s expertise on close relationships key in search to treat negative consequences of stress
“The broad range of SUNY’s scientific research is reflected in these awards and we will continue to incentivize cross-campus collaboration to promote the strength of working together as a system,” said SUNY Chancellor Nancy L. Zimpher. “Congratulations to the campuses, faculty, and students involved in these promising research projects.”
“The scope, scale, and diversity of SUNY’s research portfolio are on full display with the announcement of these awards,” said Dr. Tim Killeen, president of the Research Foundation for SUNY and SUNY’s vice chancellor for research. “Collaborative research invites industry interest and entrepreneurial opportunity that lead to innovation, new business, jobs, and public benefit. We congratulate each of the fund recipients for their visionary work.”
“These awards foster important collaboration among faculty at Stony Brook and other SUNY campuses to advance research in a variety of important scientific disciplines,” said Samuel L. Stanley, Jr. MD, President of Stony Brook University. “This is a promising exercise in bringing the best minds in SUNY together without the restriction of institutional boundaries, and I’m encouraged with each new announcement as more research initiatives are funded.”
The purpose of the SUNY Research Collaboration Fund is to support collaboration among researchers and students across SUNY’s campuses in order to enhance the collective impact of their work and ability to advance science, innovation, and economic prosperity in New York State.
At Stony Brook, Dr. Scharer will work with SUNY colleagues to advance targeted cancer therapies and Dr. Davila will collaborate with SUNY colleagues on how to treat the negative consequences of stress.
Dr. Scharer and researchers at the SUNY College of Nanoscale Science and Engineering in Albany are embarking on a nanotechnology-enabled research project that will provide the basis for identifying cancer patients who will respond well to specific chemotherapeutic regiments, thus promoting personalized medicine for the treatment of ovarian and other forms of cancer.
Dr. Scharer’s Stony Brook laboratory is investigating Cisplatin, one of the most successful antitumor drugs. Certain types of tumors show resistance to the drug, thereby making therapy ineffective. One of the main mechanisms of resistance to Cisplatin is through the repair of DNA adducts formed by cellular mechanisms.
“To date it is not possible to distinguish the different types of adducts in tumor samples to determine which adduct is associated with resistance, and my laboratory is developing reagents that will be used to accurately make this distinction,” explained Dr. Scharer. “Our reagents will make it possible to establish ways to determine how different tumors respond to Cisplatin therapy. This would make it possible to select patients who would benefit from Cisplatin and others who would not, sparing some patients unnecessary side effects from the drug and allowing them to consider alternative treatment approaches.”
Dr. Davila will collaborate with researchers at Binghamton University and Upstate Medical University on a basic research project that may lead to the development of novel treatments that target the negative consequences of stress. The research team will develop an integrative genetic, developmental, and psychological framework that links social support and improved health outcomes to develop the treatment method.
As an expert on close relationships, stress and mental health, Dr. Davila will contribute to the project by examining how early interpersonal experiences and stressors, such as a poor early caregiving environment, may lead to unhealthy support processes and poor well-being among couples.
“We will investigate caregiving environments and how those environments may affect biological response to stress, particularly for people with certain genetic profiles and how they respond to supportive – or unsupportive – couple interactions,” said Dr. Davila.
This second annual round of Research Collaboration Fund awards attracted 77 proposals. Funded projects were selected through a rigorous peer-review process. Factors considered in the evaluation included: originality and significance of the research; student involvement; industry and other outreach efforts; and the ability to attract future federal, state, philanthropic, or private funding.
About The Research Foundation for The State University of New York
The RF was founded in 1951 to serve SUNY and to capitalize on its scope, scale and diversity as an engine of New York’s innovation economy. The largest, most comprehensive university-connected research foundation in the country, the RF supports nearly $1 billion in SUNY research activity annually, providing sponsored programs administration and innovation support services to SUNY faculty performing research in life sciences and medicine; engineering and nanotechnology; physical sciences and energy; social sciences, and computer and information sciences. To learn more about the RF visit www.rfsuny.org.
About the State University of New York
The State University of New York is the largest comprehensive university system in the United States, educating nearly 463,000 students in more than 7,500 degree and certificate programs, and more than 1.8 million NYS citizens in professional development and personal enrichment programs, on 64 college and university campuses. There are nearly 3 million SUNY alumni worldwide. To learn more about how SUNY creates opportunity, visit www.suny.edu.
About Stony Brook University
Part of the State University of New York system, Stony Brook University encompasses 200 buildings on 1,450 acres. Since welcoming its first incoming class in 1957, the University has grown tremendously, now with more than 24,000 students and 2,200 faculty. Its membership in the prestigious Association of American Universities (AAU) places Stony Brook among the top 62 research institutions in North America. Kiplinger named Stony Brook the 22nd best value in public colleges for in-state students and 9th for out-of-state students. One of four University Center campuses in the SUNY system, Stony Brook University co-manages Brookhaven National Laboratory, putting it in an elite group of universities that run federal research and development laboratories. As the largest single-site employer on Long Island, Stony Brook is a driving force of the regional economy, with an annual economic impact of $4.65 billion, generating nearly 60,000 jobs, and accounts for nearly 4% of all economic activity in Nassau and Suffolk counties, and roughly 7.5 percent of total jobs in Suffolk County.
© Stony Brook University 2013