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9/1/2015 Study Shows K17 Protein Promotes CancerKeratin 17 (K17), a protein previously believed to provide only mechanical support for cancer cells, appears to play a crucial role in degrading a key tumor suppressor protein in cancer cells named p27. This finding, published in the September 1 issue of Cancer Research, is based on the work of researchers in the Department of Pathology at Stony Brook University School of Medicine. They found that K17 has the ability to enter the nucleus of cancer cells, leading to the degradation of p27. The work illustrates for the first time that a keratin can function to promote the development of cancer. Furthermore, the paper details that tumors with high levels of K17 are biologically more aggressive and have a worse prognosis than low K17 tumors.
9/1/2015 Research Team Creates Model to Predict Cellular EvolutionScientists have not been able to understand and predict how cells evolve in our bodies, and this process is important because evolving cell populations are at the core of drug-resistant infections and cancer development. Now a research team led by Gábor Balázsi, PhD, of Stony Brook University, has developed a synthetic biological model that validates computational predictions of how quickly and in what manner cells change in the presence or absence of a drug. Their findings are published in a paper in Molecular Systems Biology.
8/13/2015 Astronomers Discover 'Young Jupiter' ExoplanetThe first planet detected by the Gemini Planet Imager (GPI) from an international team of astronomers, which includes two scientists from the Department of Physics & Astronomy at Stony Brook University, is one outside earth's solar system at 100 light years away. The exoplanet is being called a "young Jupiter" by the researchers because it shares many characteristics of Jupiter. A paper outlining the full findings is published in Science.
8/12/2015 Clinical Performance Measures for Healthcare Target Underuse of Care Yet Fail to Adequately Measure OveruseClinical performance measures - quality indicators used to evaluate and motivate health care providers' performance - have taken center stage in efforts to improve quality in health care on a national level. Lead author Erika Newton, MD, MPH, Clinical Assistant Professor of Emergency Medicine at Stony Brook Medicine, and Principal Investigator Brenda Sirovich, MD, MS, of the Outcomes Group, VA Medical Center, White River Junction, VT, and the Dartmouth Institute, and colleagues examined 16 national collections of performance measures and found that more than 90 percent of 521 outpatient measures targeted underuse of care and only 7 percent addressed overuse of care. Their findings are reported in the online first edition of JAMA-Internal Medicine.
8/4/2015 Could Body Posture During Sleep Affect How Your Brain Clears Waste?Sleeping in the lateral, or side position, as compared to sleeping on one's back or stomach, may more effectively remove brain waste and prove to be an important practice to help reduce the chances of developing Alzheimer's, Parkinson's and other neurological diseases, according to researchers at Stony Brook University.
7/31/2015 Stony Brook Professor Receives Cyber Research Institute Grant to Tackle Tech Support ScamsTech Support Scams appeared first in 2008 and since then, despite various crackdowns by the Federal Trade Commission, there have been thousands of individuals who have fallen victim and lost hundreds of millions of dollars. Nick Nikiforakis, an Assistant Professor of Computer Science at Stony Brook University and member of the National Security Institute, has been awarded a $67K grant from the Cyber Research Institute (CRI) to continue his research and work in technical support scams to help this ongoing issue. The grant will fund his research project, Tools and Techniques for Understanding and Detecting Technical Support Scams, which investigates the techniques used by scammers and designs effective defense systems against those scams.
7/9/2015 Stony Brook University Receives 4th ARPA-E Grant in Six MonthsStony Brook University has received a grant from the U.S. Department of Energy's (DOE) Advanced Research Projects Agency-Energy (ARPA-E) to develop a small, highly efficient and clean natural gas generator designed for use in homes to provide electric and heating. Sotirios Mamalis, PhD, Assistant Professor in the Department of Mechanical Engineering in the College of Engineering and Applied Science, will lead the research, which is the fourth Stony Brook University energy-related research project this year to receive a prestigious ARPA-E award from the DOE.
7/9/2015 Stony Brook Receives $2.5 Million DOE Grant for Transformational Energy TechnologyA Stony Brook University research team has been awarded $2.5 million from the U.S. Department of Energy's (DOE) Advanced Research Projects Agency-Energy (ARPA-E) to develop a system that condenses water vapor from power plants in order to provide supplemental cooling for the plant and reduce water use. Led by Professor Jon Longtin, PhD, from the Department of Mechanical Engineering at Stony Brook University, the goal of the research is to condense water out of flue gas to provide additional cooling that may enable power plants to be built in dry and land-locked areas, not located near a large body of water, at a time when using open bodies of water for cooling has become a national and global concern.
7/8/2015 Stony Brook University's Demian Chapman Leads Global Shark Data Initiative- About one quarter of the world's sharks, rays and skates are threatened with extinction. The lack of comprehensive and up-to-date data on species abundance and distribution hinders efforts to protect and replenish these important and dynamic marine animals. Demian Chapman, PhD, assistant professor at the School of Marine and Atmospheric Sciences, and a multi-institutional team have kicked off the Global FinPrint initiative, the first-ever global survey to inform shark and ray conservation. The largest of its kind, FinPrint is a three-year survey of sharks and rays in coral reef ecosystems designed to provide fundamental data essential to building effective conservation programs. FinPrint is funded by Vulcan Inc. which was founded by Paul G. Allen.
7/7/2015 Advancing Research to Fight GI Cancer, Lyme Disease and Pediatric Health DisparitiesThree Stony Brook University School of Medicine faculty have received SUNY Health Network of Excellence awards to further clinical investigation of critical areas in medicine affecting populations nationally and globally. The grants total $450,000, and each award is for one-year and $150,000, effective July 1, 2016 to June 30, 2016.
6/23/2015 Evolutionary Feeding Advantages of "Warm Fish" Now Affected by Human Impacts Scientists have commonly thought that fish which evolved to become endothermic, or warm-blooded, may allow them to be more active in colder waters and thus exploit more food sources. But a new study published in the Proceedings of the National Academy of Sciences (PNAS) by Daniel Madigan, PhD, a Stony Brook University marine biologist, and colleagues nationally, reveals that this is not the case and that combined effects of overfishing and environmental changes can impact the performance of these fish.
6/22/2015 Astronomers Discover 854 Ultra-Dark Galaxies in the Famous Coma ClusterA team of researchers from Stony Brook University and the National Astronomical Observatory of Japan (NAOJ) have discovered 854 "ultra-dark galaxies" in the Coma Cluster by analyzing data from the 8.2-meter Subaru Telescope. The new discovery, published in the June 2015 edition of the Astrophysical Journal Letters, surpasses the 2014 discovery of 47 mysterious dark galaxies by more than 800 and suggests that galaxy clusters are the key environment for the evolution of these mysterious dark galaxies.
6/16/2015 Climate and Ecosystem Instability Delayed Dinosaur SuccessClimate and plant community instability may have hampered the success of dinosaurs in the tropics during the Late Triassic Period (235-201 million years ago), according to a study published in the Proceedings of the National Academy of Sciences (PNAS). This finding was reached by co-author Alan H. Turner, PhD, of Stony Brook University, and an international team of scientists by examining the sedimentary rocks and fossil record preserved in the Chinle Formation in northern New Mexico to investigate the environment in tropical latitudes during the Late Triassic.
6/15/2015 Stony Brook Enters Licensing Deal to Bring Anti-Cancer Technology to MarketStony Brook University has entered into a licensing agreement with a startup company, CadheRx Therapeutics, to develop and market an anti-cancer technology discovered by Sabine Brouxhon, MD, Clinical Associate Professor in the Department of Emergency Medicine at Stony Brook University School of Medicine. The technology involves use of an antibody-based cancer therapy that down-regulates a plethora of pathways associated with resistant disease. The approach could advance treatment for patients with many forms of cancer, including breast, colorectal, lung, skin, and other epithelial-derived cancers.
6/5/2015 Beam It Up Densely: Transporting Quantum Information Without Moving Matter A team of scientists have taken quantum teleportation - a method of communicating information from one location to another without having to physically move it - to a higher level by using certain high-dimensional states (which they dubbed "donut" states) for teleportation. Stony Brook University physicist Tzu-Chieh Wei, PhD, and colleagues nationally demonstrated that their method works, is more reliable than previous teleportation schemes, and could be a stepping stone toward building a quantum communications network. Their findings appear in Nature Communications.
6/1/2015 Critically Endangered Ocean Giant is Reproducing Without Sex in the WildAre males truly essential for reproduction? Female birds, reptiles and sharks living in captivity have sometimes surprised their keepers by giving birth even though, as far as anyone can remember, they have never been housed with a male. Scientists used DNA analysis to solve this mystery some time ago, showing that these offspring were produced by asexual reproduction, a process called parthenogenesis, or "virgin birth." Although these events have captured tremendous public interest, it was unknown if this ever occurred in wild populations of these animals.
5/28/2015 Study Suggests that Dinosaurs were Warm-BloodedDinosaurs grew as fast as your average living mammal, according to a research paper published by Stony Brook University paleontologist Michael D'Emic, PhD. The paper, to published in Science on May 29, is a re-analysis of a widely publicized 2014 Science paper on dinosaur metabolism and growth that concluded dinosaurs were neither ectothermic nor endothermic--terms popularly simplified as 'cold-blooded' and 'warm-blooded'--but instead occupied an intermediate category.
5/26/2015 Removing Mutant p53 Significantly Regresses Tumors, Improves Cancer Survival Removing accumulated mutant p53 protein from a cancer model showed that tumors regress significantly and survival increases. This finding, by an international team of cancer researchers led by Ute Moll, MD, Professor of Pathology at Stony Brook University School of Medicine, is reported in a paper published advanced online May 25 in Nature.
5/20/2015 Stony Brook Archaeologists Find the Earliest Evidence of Stone Tool Making in Cradle of HumankindStony Brook, N.Y., May 20, 2015 - Our ancestors were making stone tools even earlier than we thought--some 700,000 years older. That's the finding of the West Turkana Archaeological Project (WTAP) team--co-led by Stony Brook University's Drs. Sonia Harmand and Jason Lewis--who have found the earliest stone artifacts, dating to 3.3 million years ago, at a site named Lomekwi 3 on the western shore of Lake Turkana in northern Kenya.
5/20/2015 Stony Brook University Set To Launch Georgica Pond Research ProjectStony Brook University has partnered with a group of homeowners from the Georgica Pond community, and the East Hampton Town Trustees, to form a public-private partnership to address water quality issues on the east end of Long Island. Local residents have raised $359,000 to support the research project, which will investigate the causes of environmental degradation and the toxic algae blooms observed in Georgica Pond over the last several years. Research will be led by Dr. Chris Gobler, a professor at Stony Brook University's School of Marine and Atmospheric Sciences. Based on the research findings, the partnership will work closely with the Nature Conservancy to develop a plan of action to remediate the Georgica Pond eco-system. This plan will also help inform other communities in Long Island facing similar water quality issues.
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